Analogue-based Drug Discovery

ISBN: 9783527312573

出版社: John Wiley & Sons Inc

出版年: 2006-4

页数: 606

定价: $ 260.00

装帧: HRD

内容简介

The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them. The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.