Nanoparticulate Delivery to Cancerous Lesions

ISBN: 9780387290850

出版社: Springer Verlag

出版年: 2012-12

页数: 200

定价: $ 145.77

装帧: HRD

内容简介

This book will present the most recent advances in mathematical modeling of nanoparticulate delivery to cancerous lesions. Mathematical modeling and computer simulation of the delivery of therapeutic agents to cancerous lesions is outlined via a discussion of the essential issues, with particular attention to those involving biobarriers. Modeling of various components of drug delivery is carried out, such as tumoral hemodynamics, the covective and brownian diffusion of drug molecules and nanovector within the tumor microcirculation and tumor interstitium, cell resistance mechanisms, diffusion of drug molecules along nanochannels.