Biological Reactive Intermediates VI

副标题: Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases (Advances in Experimental Medicine and Biology)

ISBN: 9780306466595

出版社: Springer

出版年: 2001-11-01

页数: 743

定价: USD 331.00

装帧: Hardcover

内容简介

This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, recent advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair, tissue specific responses to BRIs, and human health effects of BRIs. The papers that comprise this volume were submitted by world class scientists who were in attendance at The Symposium on Biological Reactive Intermediates VI at the Universite Rene Descartes, July 16-20, 2000.