Tissue Remodeling and Epithelial Morphogenesis

ISBN: 9780123749024

出版年: 2009-10

页数: 240

定价: $ 237.30

内容简介

For more than thirty years, "Current Topics in Developmental Biology" has provided a forum for dissemination and discussion of new ideas and thought in developmental biology. Bringing together a series of articles on the structural, functional, and developmental characteristics of epithelial, this thematic volume represents a timely and valuable contribution to an exciting and multi-disciplinary field of study. Because defects in epithelial function and growth control play a major role in human disease-cancerous tumors, spina bifida, cardiac malformations, for example - this volume will be a particular interest to researchers working in cancer drug design and development and those working in therapeutic areas to treat developmental abnormalities. It includes coverage of current research findings and thought on cell-cell and cell-extracellular matrix interactions gives researchers a better understanding of the processes of remodeling and morphogenesis, which are critical to the development of drugs aimed at disrupting the early formation and proliferation of cancerous tumors. It also includes chapters that discuss the most contemporary thought on cell polarity and tissue morphogenesis, providing researchers with a better understanding of the control of cellular organization and polarity (particularly important to researchers who are developing treatments for developmental abnormalities and those working in cancer drug development). It uses a variety of animal models, allowing researchers to compare and contrast the molecular mechanisms that underlie cell-cell and cell-extracelluar matrix interactions in a variety of research models.