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St. John's Wort and its Active Principles in Depression and Anxiety

副标题: Milestones in Drug Therapy

ISBN: 9783764361600

出版社: Birkhauser

出版年: 2005-04-06

页数: 188

定价: USD 149.00

装帧: Hardcover

内容简介


Hypericum extract preparations are used extensively in many countries to treat mildly to moderately depressed patients. While this was based previously on traditional experience, extensive research over the last 10 years has given a broad preclinical and clinical basis to justify the use of Hypericum as an antidepressant. This book reviews the available data related to the biochemical, functional, and behavioural pharmacology of Hypericum and its active constituents. The clinical chapters overview the evidenced basis for its use as an antidepressant, initial data in anxiety and somatoform disorders, and the site effect profile of Hypericum and its possible relevant drug interactions. The known pharmacokinetics of the relevant constituents and the biopharmaceutical quality of commercially available Hypericum preparations are also discussed.