RNA Editing
ISBN: 9780123739223
出版社: Academic Pr
出版年: 2007-8
页数: 592
定价: $ 224.87
装帧: HRD
内容简介
RNA processing plays a critical role in realizing the full potential of a given genome. One means of achieving protein diversity is through RNA editing. A diverse array of editing events has been characterized, affecting gene expression in organisms from viruses and single cell parasites to humans and plants. The variety of editing mechanisms has required the development of many different experimental approaches, many of which are likely to be broadly applicable, particularly given the interplay between editing and other cellular processes, including transcription, splicing, and RNA silencing. This volume not only covers most of the principal methods employed in the field, but also offers innovative solutions to the significant challenges posed by these experimental systems. It presents newly developed methods. It covers topics ranging from biochemistry to bioinformatics. It includes innovative solutions to potential problems.